breen lab @ ncsu

Matthew Breen :: PhD :: C.Biol :: FSB :: Professor of Genomics

 

 

If you are interested in making a tax deductible donation to support this research please consider visiting the

North Carolina Veterinary Medical Foundation

(mention the "Cancer Genomics Fund")

Thank you.

 

 

 

This site is recommended by Nature Reviews!

Canine Karyotpye

The genome of the dog is estimated to be approximately 2.5 billion bases in size. This genetic information is divided into 78 chromosome - 38 pairs of acrocentric (single-armed) autosomes and a pair of sex chromosomes. In females both sex chromosomes are X chromosomes and in males there is one X chromosome and one Y chromosome. A typical chromosome preparation (at the metaphase stage of mitosis) from a male dog is shown below. In this preparation, the chromosomes have been banded to allow identification of chroimosome pairs.

chromosome preparation

Using multicolor FISH we are able to conclusively identify each chromosome pair and generate a karyotype of the above cell, as shown below.

chromosome karotype